Calendar slow/unresponsive after in Mountain Lion
discussions.apple.com/message/21005336#21005336
What Jamie wrote
This solved my terrible slowness, spinning beach ball issues with Calendar.
Remove the Calendar from Mail, Contacts & Calendars pref panel (just uncheck from the account). Then go into Calendar and make sure the account is removed. If its not, remove it. Delete
~/Library/Calendars/. Delete~/Library/Preferences/com.apple.iCal.plist. Go back into the Mail, Contacts & Calendars pref panel, put the calendar back. Give it some time to download.